GLP-1 Dose Calculator — Convert mg to Units (Semaglutide & Tirzepatide)

Convert your prescribed compounded GLP-1 dose from milligrams to units on a U-100 insulin syringe. Works for semaglutide, tirzepatide and any vial concentration. ⚕️ Educational

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GLP-1 Dose

mg → syringe units

mg/mL
mg

⚕️ Educational tool only — not medical advice. Always follow the exact dosing instructions from your prescriber and pharmacist.

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Enter your vial and dose to convert

How to Convert GLP-1 mg to Units

  1. Find your vial concentration (mg/mL) on the label.
  2. Enter your prescribed dose in mg.
  3. Read the units to draw on a standard U-100 insulin syringe — and the volume in mL.

mg to Units: The GLP-1 Formula

Compounded semaglutide and tirzepatide are dosed in milligrams, but you draw them with a U-100 insulin syringe marked in units. The conversion is simple: units = (dose in mg ÷ concentration in mg/mL) × 100, and the injected volume is dose ÷ concentration in mL. For example, a 0.25 mg dose from a 5 mg/mL vial is 0.05 mL = 5 units.

On a U-100 syringe, 100 units equals 1 mL, so each unit mark is 0.01 mL. Always double-check the concentration on your specific vial — concentrations vary between pharmacies, so the same dose can mean a different number of units. This is an educational converter, not medical advice; follow your prescriber's and pharmacist's instructions.

Formula & Logic

GLP-1 receptor agonists are dosed in milligrams according to a manufacturer-specified schedule rather than by body weight, which distinguishes them from most weight-related medicines. Because the pens deliver a fixed volume at a given concentration, converting between the prescribed dose in milligrams and the units or volume shown on a device is a common source of confusion — and an error here is a dosing error, not a rounding issue. The escalation schedule exists to manage gastrointestinal side effects, which are the main reason people discontinue.

Volume (mL) = Dose (mg) ÷ Concentration (mg/mL)Units on a U-100 style scale = mL × 100Weekly dose is fixed by the prescribed schedule, not by body weight

where:

concentration
mg per mL, printed on the pen or vial — varies by product and strength
dose
as prescribed, following the manufacturer's titration schedule
volume
what the device actually delivers

Assumptions: General information only, not medical advice or a prescribing tool. Always follow the prescription and the product labelling. Never adjust a dose without clinical direction, and never use a device with an unfamiliar concentration without confirming it.

Step-by-Step Example: Converting 1.0 mg to Volume

Convert a prescribed dose into the volume a pen must deliver at two concentrations.

  • Prescribed dose1.0 mg weekly
  • Pen A concentration2.0 mg/mL
  • Pen B concentration8.0 mg/mL
  1. Pen A volume: 1.0 ÷ 2.0 = 0.50 mL.
  2. On a 100-unit-per-mL scale that is 0.50 × 100 = 50 units.
  3. Pen B volume: 1.0 ÷ 8.0 = 0.125 mL.
  4. On the same scale: 12.5 units — a quarter of Pen A's volume for an identical dose.
  5. Drawing 50 units from Pen B would deliver 4.0 mg, four times the prescription.
  6. Always confirm the concentration printed on the specific device in hand.

Result1.0 mg = 0.50 mL at 2 mg/mL, but only 0.125 mL at 8 mg/mL

The fourfold difference between concentrations is exactly why volume must be recomputed whenever a product or strength changes. Carrying a remembered "number of units" from one pen to another is the specific error this calculation exists to prevent.

GLP-1 Dose FAQ

Units = (dose in mg ÷ vial concentration in mg/mL) × 100. A 0.5 mg dose from a 5 mg/mL vial is 10 units (0.1 mL) on a U-100 insulin syringe.
Because vial concentration varies. The same mg dose drawn from a 10 mg/mL vial needs half the units of a 5 mg/mL vial. Always use your own vial's concentration.
No. It's an educational converter to help you understand dosing. Always follow the exact instructions from your prescriber and pharmacist.

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✔ Written & reviewed by Dr Sam — 20+ yrs in management & research leadership📅 Last updated June 2026📚 Sources: CDC & USDA / HHS Dietary Guidelines📑 How we build & check these⚖ General information only — not medical advice